DICER1 mutation and pituitary prolactinoma

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چکیده

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منابع مشابه

[Prolactinoma].

Prolactin-secreting tumours (prolactinomas) are benign neoplasms constituting about 40 percent of all pituitary tumours. The incidence of these tumours varies with age and sex, occurring most frequently in females between 20 and 40-years-old. The clinical symptoms of prolactinomas are menstrual dysfunction and galactorrhea in women and loss of libido and potency in men. Differential diagnosis o...

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Treatment of pituitary prolactinoma reverses unresponsiveness to PDE5 inhibitor therapy in men with ED and SHPRL.

Dear Editor, Four patients with erectile dysfunction (ED) induced by pituitary prolactinoma presented to our clinic from 2007 to 2008. The patients had been misdiagnosed nearly 2 years earlier at other hospitals because severe ED was the initial symptom. None of these patients had experienced successful and satisfactory intercourse in approximately 2 years despite being treated with numerous me...

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Successful Pregnancy in a Female with a Large Prolactinoma after Pituitary Tumor Apoplexy

Pituitary apoplexy is a rare condition which may cause death of the patient in severe cases and many times leads to hypopituitarism. We report a case of apoplexy in a large prolactinoma resulting in empty sella syndrome followed by a successful pregnancy. Our patient is a 32-year-old female with a history of a macroprolactinoma for approximately 17 years who presented to our hospital with a his...

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Endometrioid Endometrial Carcinoma Indirectly Caused by Pituitary Prolactinoma: A Case Report

We present the case of a 44-year-old nulliparous woman who experienced irregular menstrual cycles for about 10 years and developed both pituitary prolactinoma and endometrioid endometrial carcinoma. In premenopausal women, hyperprolactinemia causes hypogonadism by inhibiting secretion of gonadotropin-releasing hormone and thus suppressing luteinizing hormone levels, which can cause menstrual di...

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What causes a prolactinoma to be aggressive or to become a pituitary carcinoma?

INTRODUCTION Malignant prolactinoma is an exceedingly rare endocrine tumor and cannot be diagnosed on histological grounds alone. Similarly to other neuroendocrine tumors such as pheochromocytoma, the mitoses index, Ki-67, p53, and others are utilized in helping understand whether a tumor is benign or malignant or to better predict tumor behavior. We here present the unusual case of an unfortun...

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ژورنال

عنوان ژورنال: Endocrinology, Diabetes & Metabolism Case Reports

سال: 2018

ISSN: 2052-0573

DOI: 10.1530/edm-18-0087